Background: SAM68 is a 68 kDa protein that is phosphorylated on tyrosine and functions as a substrate for Src family tyrosine kinases during mitosis. SAM68 also associates with several SH2 and SH3 domain-containing signaling proteins, such as GRB2 and PLC γ1. Originally cloned as Ras GAP-associated p62, further investigations have shown that Sam 68 and Ras GAP-associated p62 are not antigenically related, nor are they encoded by the same gene.
Description: Rabbit polyclonal to SAM68
Immunogen: KLH conjugated synthetic peptide derived from SAM68
Specificity: ·Reacts with Human, Mouse and Rat.
.·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 68 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
