Background: Tenomodulin (TEM), also designated chondromodulin-I-like protein (CHM-1L), myodulin or tendin, acts as an angiogenesis inhibitor. It is a single-pass type II membrane protein that belongs to the chondromodulin family of proteins. The deduced 317 amino acid protein contains an N-terminal transmembrane domain and a putative antiangiogenic domain comprised of eight cysteines. Human Tenomodulin shares 96% amino acid identity with mouse Tenomodulin, and it shares 65% identity in a 65-amino acid C-terminal stretch with chondromodulin I. Tenomodulin is expressed in skeletal muscle, eye, whole rib and dense connective tissues, such as epimysium and tendon.
Description: Rabbit polyclonal to Tenomodulin
Immunogen: KLH conjugated synthetic peptide derived from Tenomodulin
Specificity: ·Reacts with Human, Mouse, Pig, Dog and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 37 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
