Background: Teratocarcinoma-derived growth factor (TDGF)-1 gene encodes a protein known as Cripto-1. This gene is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers. It could play a role in the determination of the epiblastic cells that give rise to the mesoderm. Cripto-1 overexpression is characteristic of human gastric and colorectal carcinomas.
Description: Rabbit polyclonal to Cripto-1
Immunogen: KLH conjugated synthetic peptide derived from Cripto-1
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 21 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/100-500;
·Immunocytochemistry: 1/100-200;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
