Background: Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. CNGA2 belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family and contains one cyclic nucleotide-binding domain. It may be involved in odorant signal transduction. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.
Description: Rabbit polyclonal to CNGA2
Immunogen: KLH conjugated synthetic peptide derived from CNGA2
Specificity: ·Reacts with Human, Mouse, Rabbit, Dog and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 76 kDa;
·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;
·Immunocytochemistry: 1/100-200;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
