Background: The semaphorins make up a family of inhibitory axon guidance molecules that include secreted, transmembrane, and GPI anchored extracellular molecules. Via their interaction with Plexin/Neuropilin receptor complexes, the semaphorins are involved in regulating axon guidance by inhibiting axons from growing toward incorrect targets. Semaphorin 3F belongs to the class 3 secreted group of molecules and shows ubiquitous expression in a range of neuronal and non-neuronal tissues including brain, mammary gland, liver, kidney, lung, spleen, muscle and heart. The role of the semaphorins in non-neuronal tissues is poorly characterised.
Description: Rabbit polyclonal to Sema3F
Immunogen: KLH conjugated synthetic peptide derived from Sema3F
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 88 kDa;
·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;
·Immunocytochemistry: 1/100-500;
· ELISA:1/500;
·Optimal working dilutions must be determined by the end user.
