Background: CD147 (also called Basigin; BSG; Leukocyte activation antigen M6; Collagenase stimulatory factor; Extracellular matrix metalloproteinase inducer; EMMPRIN; 5F7; Tumor cell-derived collagenase stimulatory factor; TCSF; OK blood group antigen) Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.
Description: Rabbit polyclonal to CD147
Immunogen: KLH conjugated synthetic peptide derived from CD147
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 42 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/100-500;
·Immunocytochemistry: 1/100-200;
·ELISA: 1/1000;
·Optimal working dilutions must be determined by the end user.
