Background: Chemokine receptors belong to the superfamily of G protein coupled receptors, which regulate the trafficking and activation of leukocytes and operate as co-receptors in the entry of HIV1. CXCR1 is the receptor for interleukin-8, which is a powerful neutrophil chemotactic factor. Binding of IL-8 to CXCR1 causes activation of neutrophils. CXCR1 expression also plays an important role in many inflammatory processes.
Description: Rabbit polyclonal to CXCR1
Immunogen: KLH conjugated synthetic peptide derived from CXCR1
Specificity: ·Reacts with Human, Mouse, Rabbit, Dog, Cow and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 42 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/100-500;
·Immunocytochemistry: 1/200;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
