Background: The Jagged1 is a ligand for multiple Notch receptors and is involved in the mediation of Notch signaling. Jagged1 may be involved in cell-fate decisions during hematopoiesis and seems to be involved in early and late stages of mammalian cardiovascular development. Jagged1 inhibits myoblast differentiation by similarity and enhances fibroblast growth factor-induced angiogenesis (in vitro).
Description: Rabbit polyclonal to Jagged1
Immunogen: KLH conjugated synthetic peptide derived from Jagged1
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 150 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
