Background: Cyclin is essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions. Interacts with the CDK2 and CDC2 protein kinases to form a serine/threonine kinase holoenzyme complex. The cyclin subunit imparts substrate specificity to the complex. When associated with CDK2 (but not with CDC2), interacts with SCAPER. Subcellular location in Nucleus. Cytoplasm. Belongs to the cyclin family. Cyclin AB subfamily.
Description: Rabbit polyclonal to Cyclin A2
Immunogen: KLH conjugated synthetic peptide derived Cyclin A2
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 48 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
