Background: The cell source growth factor 1: tend to turn the factor CXCL12 to have tend of mightiness to the lymphoid cell to turn the function and rise the important function in the growth.The CXCL12 leading builds the blood stem cell in embryo develop from embryo's liver to the change residence of marrow. CXCL12 can expression in many tissues ( include the brain, thymus gland, heart, lung, liver, kidney, marrow, spleen). Chemokine_CXC: 1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; many members contain an RCxC motif which may be a general requirement for binding to CXC chemokine receptors; those with the ELR motif are chemotatic for neutrophils and have been shown to be angiogenic, while those without the motif act on T and B cells, and are typically angiostatic; exist as monomers and dimers, but are believed to be functional as monomers; found only in vertebrates and a few viruses.
Description: Rabbit polyclonal to SDF-1
Immunogen: KLH conjugated synthetic peptide derived from SDF-1
Specificity: ·Reacts with Human, Mouse, Dog and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 10 kDa;
·Immunohistochemistry (Frozen/paraffin tissue section): 1/50-200;
·Immunocytochemistry: 1/100;
·ELISA: 1/500;
· Optimal working dilutions must be determined by the end user.
