Background: Hepatitis B Virus Surface Antigen, Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase.
Description: Mouse monoclonal to HBsAg
Immunogen: Human Hepatitis B Surface Antigen protein
Specificity: ·Recognizes Human Hepatitis B Surface Antigen in Immunohistochemiscal staining.
·Isotype: IgG
Application: ·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunofluorescence: 1/100;
·Optimal working dilutions must be determined by the end user.
