Background: The endothelium represents the layer of thin specialized epithelium made up of a simple squamous layer of cells that line the interior surface of blood vessels to form an interface between circulating blood in the lumen and the rest of the vessel wall. Endothelial cells line the entire circulatory system and are involved in many aspects of vascular biology, including blood clotting, inflammation, swelling, vasoconstriction, vasodilation and atherosclerosis. Endothelial cells also control the passage of materials and the transit of white blood cells into and out of the bloodstream. In some organs, endothelial cells are highly differentiated to perform more specialized filtering functions. Examples of such unique endothelial structures include the renal glomerulus and the blood-brain barrier. RECA-1, also designated rat endothelial cell antigen-1, is a cell surface antigen which is expressed by all rat endothelial cells.
Description: Rabbit polyclonal to RECA1
Immunogen: KLH conjugated synthetic peptide derived from RECA1
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Optimal working dilutions must be determined by the end user.
