Background: D4ST (dermatan 4-sulfotransferase 1), also known as CHST14 (carbohydrate sulfotransferase 14), is a 376 amino acid single-pass type II membrane protein that localizes to the golgi apparatus and belongs to the sulfotransferase family. Expressed in a variety of tissues with highest expression in placenta, thyroid, uterus and pituitary gland, D4ST functions to specifically catalyze the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate, an event that is necessary for dermatan sulfate synthesis. The gene encoding D4ST maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome.
Description: Rabbit polyclonal to CHSY14
Immunogen: KLH conjugated synthetic peptide derived from CHSY14
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 43 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
