Background: TRP2(tyrosinase related protein 2) involved in regulating eumelanin and phaeomelanin levels. [FUNCTION] Involved in regulating eumelanin and phaeomelanin levels. [CATALYTIC ACTIVITY] L-dopachrome; 5,6-dihydroxyindole-2-carboxylate. [COFACTOR] Binds 2 zinc ions per subunit. [SUBUNIT] Tyrosinase, TYRP1 and TYRP2 may form a multienzyme complex. [SUBCELLULAR LOCATION] Melanosome membrane; Single-pass type I membrane protein. [TISSUE SPECIFICITY] Melanocytes and retinal pigmented epithelium.
Description: Rabbit polyclonal to TRP2
Immunogen: KLH conjugated synthetic peptide derived from TRP2
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 59 kDa;
·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;
·Immunocytochemistry: 1/100-500;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
